Lewyt College of Veterinary Medicine

ABOUT

Ravinder Sappal, DVM, MVSc, MSc, PhD.

Assistant Professor of Veterinary Toxicology

Email: Ravinder.Sappal@liu.edu

Dr. Ravinder Sappal received her Veterinary degree from Punjab Agricultural University in India. After completing a clinical internship, she obtained MVSc in Veterinary Pharmacology and Toxicology and moved to Canada to pursue graduate studies in Veterinary Toxicology. She received her MSc and PhD in aquatic toxicology from the Atlantic Veterinary College (AVC), University of Prince Edward Island, Canada, and later completed postdoctoral fellowships at the AVC and Thompson Rivers University in British Columbia, Canada. During her graduate and postdoctoral studies, she was a recipient of several scholarships and fellowships, and her research work has been listed as Editor’s Choice in the journal of Aquatic Toxicology. Her research is multi-sectorial and involves collaboration with aquaculture and food industries, and not-for-profit non-governmental organizations.

Dr. Sappal’s research is both basic and applied with emphasis on environmental toxicology and aquatic animal health. She uses bioanalytical, molecular, and biochemical techniques to examine interactions between animals and their environment. Her current research focuses on, (ii) understanding the role of nutrition in the regulation of physiological responses to environmental stressors in fish, and (ii) elucidating the interaction of nutrition and environmental stressors on mitochondrial physiology.

Publications - (selected manuscripts)

  • Kamunde C, Wijayakulathilake Y, Okoye C, Chinnappareddy N, Kalvani Z, Tetteh P, Heuvel M, Ravinder Sappal, Stevens D, Effect of skeletal muscle mitochondrial phenotype on H2O2 emission, Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, Volume 271, 2024, 110940, ISSN 1096 4959, https://doi.org/10.1016/j.cbpb.2024.110940.
  • Kamunde C, Sappal R, Melegy TM. Evaluating brown seaweed supplementation in feed for Atlantic salmon smolts. Global Aquaculture Advocate. www.aquaculturealliance.org/advocate/evaluating-brown-seaweed-supplementation-in-feed-for-atlantic-salmon-smolts/,2020.
  • Kamunde C, Sappal R, Melegy TM. Brown seaweed (AquaArom) supplementation increases food intake and improves growth, antioxidant status and resistance to temperature stress in Atlantic salmon, Salmo salar. PLoS One. https://doi.org/10.1371/journal.pone.0219792, 2019.
  • Sappal R, Fast M, Purcell S, et al. Copper and hypoxia modulate transcriptional and mitochondrial-functional biochemical responses in warm acclimated rainbow trout (Oncorhynchus mykiss). Environmental Pollution 211: 291-306, 2016.
  • Sappal R, Fast M, Stevens D, et al. Effects of copper, hypoxia and acute temperature shifts on mitochondrial oxidation in rainbow trout (Oncorhynchus mykiss) acclimated to warm temperature. Aquatic Toxicology 169: 46-57. EDITOR’S CHOICE, 2015.
  • Sappal R, MacDougald M, Fast M, et al. Alterations in mitochondrial electron transport system activity in response to warm acclimation, hypoxia-reoxygenation and copper in rainbow trout (Oncorhynchus mykiss). Aquatic Toxicology 165: 51-63, 2015.
  • Sappal R, Sidhu PK, Choudahry RK, et al. Determination of optimum dosage schedules of danofloxacin following two extravascular routes of administration in buffalo calves (Bubalus bubalis). Online Journal of Veterinary Research. 19: 90-101, 2015.
  • Sappal R, MacDonald N, Fast M, et al. Interactions of copper and thermal stress on mitochondrial bioenergetics in rainbow trout (Oncorhynchus mykiss). Aquatic Toxicology 157: 10-20, 2014.
  • Sappal R, MacDougald M, Stevens D, et al. Copper alters the effect of temperature on mitochondrial bioenergetics in rainbow trout (Oncorhynchus mykiss). Archives of Environmental Contamination and Toxicology 66: 430-440, 2014.
  • Sappal R, Kamunde C. Internal bioavailability of waterborne and dietary zinc in rainbow trout, Oncorhynchus mykiss: preferential detoxification of dietary zinc. Aquatic Toxicology. 93: 166-176, 2009.
  • Sappal R, Choudahry RK, Sandhu HS, et al. Pharmacokinetics, urinary excretion and plasma protein binding of danofloxacin following intravenous administration in buffalo calves (Bubalus bubalis). Veterinary Research Communications March 19 PMID: 19296232, 2009.
  • Sappal R, Burka J, Dawson S, et al. Bioaccumulation and subcellular partitioning of zinc in rainbow trout (Oncorhynchus mykiss): cross-talk between waterborne and dietary uptake. Aquatic Toxicology. 91: 281-362, 2008.
  • Sappal R, Choudahry RK, Sandhu HS, et al. Pharmacokinetics, urinary excretion, protein binding and pharmacodynamics of danofloxacin following intravenous administration in buffalo calves (Bubalus bubalis). Journal of Veterinary Pharmacology and Therapeutics 29: 268, 2006.