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Faculty

Jaclyn Cusumano, PharmD, BCIDP

Assistant Professor of Pharmacy Practice

Pharm.D., University of Rhode Island

Description

Dr. Jaclyn Cusumano received her Doctor of Pharmacy at the University of Rhode Island in 2015.  She then completed her PGY1 Pharmacy Practice Residency at Thomas Jefferson University Hospital in Philadelphia, Pennsylvania.  After residency, Dr. Cusumano worked as an antimicrobial stewardship pharmacist at Sturdy Memorial Hospital in Attleboro, Massachusetts, where she assisted in developing the hospital’s first antimicrobial stewardship program.  Dr. Cusumano then went on to complete a two-year infectious diseases pharmacotherapy research fellowsip at the Providence VA Medical Center, where she also held an Adjunct Assistant Professor position at the University of Rhode Island.  Dr. Cusumano completed her teaching certificate with the University of Rhode Island during fellowship.  

Dr. Cusumano’s research is focused on the discovery of ideal antimicrobial regimens for multidrug resistant bacteria, including penicillin-resistant ampicillin-susceptible Enterococcus faecalis and Klebsiella pneumoniae, as well as identification of antimicrobial pharmacodynamic targets through in vitro modeling.  Her research aims to clinically translate in vitro findings to advance therapeutic drug monitoring practices.

Specialties

Infectious diseases, multidrug resistant bacteria, antimicrobial stewardship

Publications

  • Avvari SK, Cusumano JA, Jogiraju VK, Manchandani P, Taft DR. PBPK Modeling of azithromycin systemic exposure in a Roux-en-Y gastric bypass surgery patient population. Pharmaceutics. 2023, 15(11); doi.org/10.3390/pharmaceutics15112520.
  • Cusumano JA, Daffinee KE, Ugalde P, Peti W, Arthur M, Desbonnet C, Rice L, LaPlante KL, Garcia-Solache M. Penicillin-binding proteins and alternative dual beta-lactam combinations for serious Enterococcus faecalis infections with elevated penicillin MICs. Antimicrob Agents Chemother. 2023;e0087122. doi: 10.1128/aac.00871-22.
  • Cusumano JA, Funk O, Defrank A, Lerner P, Tanprayoon M, Vasa C, Mazo D. The role of an infectious diseases faculty pharmacist and pharmacy students on an antimicrobial stewardship team at a community non-teaching hospital. J Pharm Practice. 2022;8971900221134648. doi:10.1177/08971900221134648
  • Cusumano JA, Daffinee KE, Piehl EC, Garcia-Solache M, Desbonnet C, Rice LB, LaPlante KL. Meropenem plus ceftaroline is active against Enterococcus faecalis in an in vitro pharmacodynamics model using humanized dosing simulations. Antimicrob Agents Chemother. 2022;66(10):e0042622. doi: 10.1128/aac.00426-22.
  • Markovskaya Y, Gavioli EM, Cusumano JA, Glatt A. Secondary bacterial infections and the impact on antimicrobial resistance during the COVID-19 pandemic. Antimicrob Steward Healthc Epidemiol. 2022;2(1):1-13. doi.org/10.1017/ash.2022.253
  • Cusumano JA, Khan R, Shah Z, Philogene C, Harrichand A, Huang V. Penicillin plus ceftriaxone versus ampicillin plus ceftriaxone synergistic potential against clinical Enterococcus faecalis blood isolates. Microbiol Spectr. 2022;10(4):e00621-22. doi.org/10.1128/spectrum.00621-22
  • Dupper AC, Malik Y, Cusumano JA, Nadkarni D, Banga J, Berbel Caban A, Twyman K, Obla A, Patel D, Mazo D, Altman DR. Longer steroid treatment increases secondary bloodstream infection risk among patients with COVID-19 requiring intensive care. Infect Dis Clin Pract. 2022;30(4). doi: 10.1097/IPC.0000000000001188
  • Kish T, Gim S, Pharm A, Cusumano J, Orcheretyaner E, Quattrocchi E, Hareez L, Chen M, Plakogiannis R. Programme Description: Virtual APPE grand rounds: A learning activity to enhance remote rotations during the COVID-19 pandemic. Pharmacy Education. 2021;11. doi.org/10.46542/pe.2021.211.651655
  • Neeli H, Hanna N, Abduljalil, Cusumano JA, Taft DR. Application of physiologically based pharmacokinetic‐pharmacodynamic modeling in preterm neonates to guide gentamicin dosing decisions and predict antibacterial effect. J Clin Pharmacol. 2021;61(10):1356-1365. doi.org/10.1002/jcph.1890
  • Cusumano JA, Dupper AC, Malik, Y, Gavioli EM, Banga J, Caban A, Nadkarni D, Vasa CV, Mazo D, Altman DR. Staphylococcus aureus bacteremia in patients infected with COVID-19: A cohort study. Open Forum Infect Dis. 2020;7(11):ofaa518. doi.org/10.1093/ofid/ofaa518
  • Cusumano JA, Hermenau M, Gaitanis MM, Travis M, LaPlante KL, Tran T, McConeghy KW. Evaluation of post-flexible cystoscopy urinary tract infection rates. Am J Hosp Pharm. 2020;77(22):1852-1858. doi: 10.1093/ajhp/zxaa270.
  • Cusumano JA, Klinker KP, Huttner A, Luther MK, Roberts JA, LaPlante KL. Towards precision medicine: therapeutic drug monitoring-guided dosing of vancomycin and β-lactam antibiotics to maximize efficacy and minimize toxicities. Am J Hosp Pharm. 2020;77(14):1104- 1112. doi: 10.1093/ajhp/zxaa128
  • Gavioli EM, Sikorska G, Man A, Rana J, Cusumano JA. Tocilizumab Utilization for COVID- 19: A Case Series. Infect Dis Clin Pract. 2020;28(6):349-353. doi:10.1097/IPC.0000000000000890
  • Cusumano JA, Daffinee KE, Luther MK, Lopes V, Caffrey AR, LaPlante KL. Carbapenem- resistant Klebsiella pneumoniae have low potential to form biofilm. Diagn Microbiol Infect Dis. 2019;95(4):114877. doi: 10.1016/j.diagmicrobio.2019.114877.
  • Beganovic M, Cusumano JA, Lopes V, LaPlante KL, Caffrey AR. Comparative effectiveness of nafcillin or oxacillin, cefazolin, and piperacillin/ tazobactam against methicillin-sensitive Staphylococcus aureus bacteremia in the Veterans Affairs. Open Forum Infect Dis. 2019; 6(7):ofz270. doi.org/10.1093/ofid/ofz270LaPlante
  • KL, Cusumano JA, Tillotson G. Colistin for the treatment of multidrug-resistant infections. Lancet Infect Dis. 2018;18(11):1174-1175. doi: 10.1016/S1473-3099(18)30611-X.

Grants

  • Cusumano JA (PI). Basilea Pharmaceutica. “The role of ceftobiprole in treating Enterococcus faecalis bloodstream infections. ($81,534). October 2023-September 2024.
  • Cusumano JA (PI). American Association of Colleges of Pharmacy (AACP) New Investigator Award. “Innovative assessment of penicillin plus ceftriaxone against Enterococcus faecalis” ($8750). March 2021 - September 2022.

Book Chapter

  • Cusumano JA. Antimicrobial Prophylaxis for Post-Urologic Surgery UTI. In:Infectious Diseases Self-Assessment Program (IDSAP) Book 1: Abdominopelvic Cavity Infections and Antimicrobial Toxicities. American College of Clinical Pharmacy. PSAP Pharmacotherapy Self-Assessment Program: Module. Kansas City, MO: ACCP, 2022.

Lectures and Presentations

Platform Presentations

  • Nwoye A, Bocanegra, Khan R, Shah Z, Cusumano JA. Penicillin plus ceftaroline against Enterococcus faecalis blood isolates lacking ampicillin plus ceftriaxone activity. IDWeek 2022. Abstract #1522. October 21, 2022.
  • Cusumano JA, Daffinee KE, LaPlante KL. Carbapenem based dual beta-lactam combinations for Enterococcus faecalis. Annual Infectious Diseases Pharmacy Fellowship Forum. June 2019. Providence, RI.
  • Cusumano JA, Hermenau M, Timothy T, Travis M, Gaitanis G, LaPlante KL, McConeghy KW. Surgical antimicrobial stewardship: evaluation of antimicrobial prophylaxis pre-flexible cystoscopy. European Congress of Clinical Microbiology and Infectious Diseases. April 16, 2019. Amsterdam, Netherlands. Abstract #4142.
  • Cusumano JA, Daffinee KE, Luther MK, Lopes V, Caffrey AR, LaPlante KL. Carbapenem- resistant Klebsiella pneumoniae have low potential to form biofilm. Annual Infectious Diseases Pharmacy Fellowship Forum. June 2018. Buffalo, NY.
  • Cusumano JA, Francos G, Chaballa M. Assessing the Impact of Telemonitoring on Hypertension Management in Kidney Transplant Recipients. Annual Eastern States Pharmacy Resident Conference. May 2016. Hershey, PA.

Poster Presentations
  • Hedvat J, Gitman MR, Nwoye A, Chen L, Martin C, Wang M, Vasa C, Cusumano JA. Implications of Enterococcus faecalis penicillin susceptibility in patients with bacteremia. Boston, MA. IDWeek 2023. Oct, 12, 2023. Abstract #184.
  • Cusumano JA, Khan R, Shah Z, Huang V. In vitro efficacy of penicillin plus ceftriaxone against Enterococcus faecalis. 123rd Annual Meeting of American Association of Colleges of Pharmacy. July 2022. Grapevine, TX.
  • Khan R, Shah Z, Huang V, Cusumano JA. Penicillin plus ceftriaxone against Enterococcus faecalis in vitro time-kill studies. IDWeek 2021. Virtual. September 2021. Abstract #681.
  • Malik Y, Dupper A, Cusumano JA, Patel D, Twyman K, Altman D, Mazo D, Chasan R. Use of (1-3)-β-D-Glucan assay for diagnosis of candidemia in patients hospitalized with SARS-CoV-2 Infection. IDWeek 2021. Virtual. September 2021. Abstract #316.
  • Kish T, Gim S, Pham A, Cusumano J, Ocheretyaner E, Quattrocchi E, Hareez LB, Plakogiannis R. Virtual APPE grand rounds: a learning activity to enhance remote rotations during the COVID-19 pandemic. AACP Meeting (virtual), July 2021.
  • Farooqi S, Zaki L, Vasa C, Lerner P, Satti FG, Mazo DS, Cusumano JA. Assessing the impact of pharmacy students on an antimicrobial stewardship team at a non-teaching community hospital. American Society of Health-System Pharmacists 2020 Midyear Clinical Meeting. Virtual. December 2020.
  • Cusumano JA, Appaneal H, Lopes V, LaPlante KL, Caffrey A. Comparative effectiveness of empiric antistaphylococcal penicillins versus cefazolin in methicillin-susceptible Staphylococcus aureus bacteraemia. European Congress of Clinical Microbiology and Infectious Diseases 2020. Poster Abstract Published in ECCMID 2020 Abstract Book. Meeting Cancelled.
  • Cusumano JA, Daffinee KE, LaPlante KL. Ertapenem plus ceftriaxone or ceftaroline dual beta- lactam combination for Enterococcus faecalis. IDWeek 2019. October, 4, 2019. Washington DC. Abstract #1559.
  • Bodo EC, Caffrey A, Lopes V, Cusumano JA, Puzniak LA, McCann E, LaPlante KL. Evaluation of multidrug-resistant Pseudomonas aeruginosa isolates in patients receiving ceftolozane/tazobactam. IDWeek 2019. October 5, 2019. Washington DC. Abstract #2291.
  • Cusumano JA, Bodo EC, Lopes V, McConeghy KW, Puzniak LA, McCann E, LaPlante KL, Caffrey AR. Ceftolozane/tazobactam utilization in the national Veterans Affairs (VA) healthcare system. 35th International Conference on Pharmacoepidemiology & Therapeutic Risk Management. August 28, 2019. Philadelphia, PA. Poster #120.
  • Cusumano JA, Bodo EC, Lopes V, McConeghy KW, Puzniak LA, McCann E, Caffrey AR, LaPlante KL. Treatment with ceftolozane/tazobactam in the national Veterans Affairs (VA) healthcare system. MAD-ID 2019 Annual Meeting. May 2019. Orlando, FL.
  • Cusumano JA, Daffinee KE, Bodo EC, LaPlante KL. Alternative dual beta-lactam combinations for Enterococcus faecalis. European Congress of Clinical Microbiology and Infectious Diseases. April 16, 2019. Amsterdam, Netherlands. Abstract #4001.
  • Murthy A, Bodo EC, LaPlante KL, Cusumano JA. Trends in antimicrobial stewardship interventions at the Providence VA Medical Center. American Society of Health-System Pharmacists 2018 Midyear Clinical Meeting. December 2018 Anaheim, CA.
  • Nadeau MJ, Cusumano JA, LaPlante KL, Bodo EC. Seasonality of antimicrobial stewardship interventions. American Society of Health-System Pharmacists 2018 Midyear Clinical Meeting. December 2018. Anaheim, CA.
  • Cusumano JA, Daffinee KE, Luther MK, Lopes V, Caffrey AR, LaPlante KL. Relationship between Klebsiella pneumoniae biofilm formation to antimicrobial resistance. IDWeek 2018. San Francisco, CA. Abstract #71726.
  • Beganovic M, Cusumano JA, Lopes V, LaPlante KL, Caffrey AR. Comparative effectiveness of nafcillin or oxacillin, cefazolin, and piperacillin/tazobactam against methicillin-sensitive Staphylococcus aureus bacteremia in the Veterans Affairs. IDWeek 2018. San Francisco, CA. Abstract #73397.
  • Cusumano JA, Daffinee KE, Luther MK, Lopes V, Caffrey AR, LaPlante KL. Relationship between Klebsiella pneumoniae biofilm formation to antimicrobial resistance. MAD-ID 2018 Annual Meeting. May 2018. Orlando, FL.
  • Mortrude GC, Cusumano JA, Morrill HJ, LaPlante KL. Comparing interventions made by the Providence VAMC antimicrobial stewardship team in the years 2014 and 2016. American Society of Health-System Pharmacists 2017 Midyear Clinical Meeting and Exhibition Poster Session. Orlando, FL.
  • Cusumano JA, Morlino AM, Moyer A. Daptomycin non-susceptible Staphylococcus aureus: a case report. American Society of Health-System Pharmacists 2015 Midyear Clinical Meeting and Exhibition Poster Session; and UHC Pharmacy Council Meeting 2015. New Orleans, LA.
  • Cusumano JA, Morrill HJ, Gaitanis MM, LaPlante KL. Evaluation of an antimicrobial stewardship team’s interventions based on infection type. American Society of Health-System Pharmacists 2014 Midyear Clinical Meeting and Exhibition Poster Session. Anaheim, CA.
  • Cusumano JA, Fox M. Script Your Future Blood Pressure Clinic: Lambda Kappa Sigma, Xi Chapter. Poster Presentation: Presented at Lambda Kappa Sigma’s Centennial Celebration National Convention. July 2013. Boston, MA. (1st place in poster competition)
  • Cusumano JA, Coomes A, Chen X, Louie E, Chen E. Studying the Phenotypic Differences of Metastatic Stem-Like Breast Cancer Cells in Three-Dimensional Cultures. NYSTEM and HHMI summer undergraduate research program poster session. August 2011. Stony Brook, NY.

Educational Presentations

  • Cusumano JA. Beta-lactam allergies and cefepime dosing. Mount Sinai Queens hospitalists and physician assistant team meeting. August 2022. Queens, NY
  • Cusumano JA. Vancomycin dosing in hemodialysis. Mount Sinai Queens hospitalists and physician assistant team meeting. March 2022. Queens, NY
  • Cusumano JA. Vancomycin dosing and area under the curve. Mount Sinai Queens hospitalists and physician assistant team meeting. February 2022. Queens, NY.
  • Cusumano JA, Gavioli EM. Keeping safe while treating the COVID-19 patient. Virtual ACPE Accredited CE Lecture. June 2020. Brooklyn, NY.

Honors/Awards

  • American Association of Colleges of Pharmacy, New Investigator Award, 2021
  • Recipient, European Congress of Clinical Microbiology and Infectious Diseases 2019 & 2020 Travel Grant
  • Recipient, IDWeek 2018 & 2019 Travel Award
  • Recipient, MAD-ID (Making a Difference in Infectious Diseases) 2018 & 2019

Professional Affiliations

  • American Society of Microbiology, Member
  • New York State Council of Health-System Pharmacists (NYSCHP) Chapters: ROYALS, New York City
  • American College of Clinical Pharmacy, Member
    • Infectious Diseases PRN, Member
      • Research Committee, Member
  • American Association of Colleges of Pharmacy, Member
  • Infectious Diseases Society of America, Member
  • Making a Difference in Infectious Diseases, Member
  • Society of Infectious Diseases Pharmacists, Member
    • Inter-Organizational Engagement Committee, Chair
  • European Society of Clinical Microbiology and Infectious Diseases, Member
  • Lambda Kappa Sigma, Faculty Advisor, Alpha Eta Chapter