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Faculty


Ahmed Abu Fayyad

Ahmed Abu Fayyad, Ph.D., R.Ph

Associate Professor of PharmaceuticsDivision of Pharmaceutical Sciences

Ph.D. Pharmaceutics, University of Louisiana Monroe College of Pharmacy, Monroe, LA, USB.Sc. Pharmacy, Isra University College of Pharmacy, Amman-Jordan

Description

Dr. Abu Fayyad is a passionate pharmacy educator, pharmacist, and pharmaceutical product development scientist. Before joining LIU Pharmacy, he was an Assistant Professor of Pharmaceutics at the Chicago State University College of Pharmacy (CSU-COP).

At CSU COP, he taught and coordinated several pharmaceutics courses and initiated a research program in three themes, all translational/clinical pharmaceutics oriented: (1) advancing new drug delivery systems (505(b)2 FDA approval pathway-focused)/emerging modalities and technology for cancer therapy into the level of IND-enabling studies, through collaboration with top tier institutions to fast translate novel assets into clinical development, (2) establishing clinical compounding and product development facility, and (3) regulatory FDA-focused program regarding tools/methods/centers/policies for accelerating the development and approval process of new pharmaceutical products.

During his tenure at CSU-COP, Dr. Abu Fayyad has worked and secured extramural funding from the pharmaceutical industry Pfizer working on pre-clinical development of first-in-class cancer therapeutics. Further to support his work, he co-founded a biotech firm gathering industry experts’ colleagues who complement his experience and has collaborated with top tier academic labs doing research in cancer therapeutics to fast bridge their discoveries into translational aspects and subsequently into clinical development avoiding the so-called the Valley of Death. His scholarly work was recognized by several international organizations; the AACP to name a few. Moreover, he played an integral role in establishing a new intensive NAPLEX review course for the P4 students to tackle the national trend of the low NAPLEX passing rate during the last few years.

Dr. Abu Fayyad worked also as a Scientist, Product Development at several pharmaceutical companies, more recently, Modavar Pharmaceuticals, the US branch of Cadila Pharmaceuticals. At Modavar, with his team, they established a cGMP pharmaceutical product development facility for 505(b)(2) FDA approval pathway for reformulating and developing new and modified dosage forms/products for an already FDA-approved small molecules drug. Several products were developed at the established facility and submitted to the FDA for review. Dr. Abu Fayyad is also an active pharmily member, has served as a faculty advisor for several pharmacy students’ organizations, and was on several department, college, and university levels committees.

Dr. Abu Fayyad is a registered pharmacist in the state of Illinois. He is an active member of several national and international pharmaceutical organizations.

Specialties

  • Design and development of new pharmaceutical products using emerging technologies through 505(b)2 FDA approval pathway.
  • Preclinical IND-enabling to clinical NDA CMC development.
  • Regulatory, FDA/state board of pharmacy, in areas of establishing tools/methods/centers/policies to accelerating the development and approval process of new pharmaceutical products.
  • Establishing a cGMP facility for compounding clinical batches.

Publications

  • Elsanhoury, R., et al “AI & experimental-based discovery and preclinical IND-enabling studies of selective BMX inhibitors for development of cancer therapeutics, International Journal of Pharmaceutics, vol 645 (2023): 123384.
  • Salawi, A., et al “Pharmaceutical characterization and dissolution behavior of ibuprofen/Soluplus solvent cast films.” Tropical Journal of Pharmaceutical Research February 2023; 22 (2): 227-232.
  • Tauseef, M., et al. The Development of Biologics from the Perspective of the Pharmaceutical Industry. In: Z. Feng, H. Xie, A. Malhotra, and C. Yang [eds.] Biologics and Biosimilars, Drug Discovery and Clinical Applications. CRC Press. 2022.
  • Salawi, A., et al. "Preparation and Characterization of Aqueous Vitamin E/Soluplus® Dispersions for Film Coating Applications." Drug Development and Industrial Pharmacy, 2021, 1-11.
  • Kamal, Mohmmad et al. “Development and characterization of curcumin-loaded solid self-emulsifying drug delivery system (SEDDS) by spray drying using Soluplus® as solid carrier. Powder Technology, Volume 369, 1 June 2020, 137-145.
  • Shakhwar, Sara et al. Development and evaluation of paclitaxel nanoemulsion for cancer therapy” Pharm Dev Technol. 2019 Dec 26:1-7.
  • Abu-Fayyad, Ahmed et al. “Development and in-vitro characterization of nanoemulsions loaded with paclitaxel/γ- tocotrienol lipid conjugates.” International journal of pharmaceutics vol. 536,1 (2018): 146-157.
  • Abu-Fayyad, Ahmed, and Sami Nazzal. “Synthesis, characterization, and in-vitro antitumor activity of the polyethylene glycol (350 and 1000) succinate derivatives of the tocopherol and tocotrienol isomers of Vitamin E.” International journal of pharmaceutics vol. 519,1-2 (2017): 145-156.
  • Abu-Fayyad, Ahmed, and Sami Nazzal. “Synthesis, physiochemical characterization, and in vitro antitumor activity of the amide and pH cleavable hydrazone conjugates of γ-tocotrienol isomer of vitamin E with methoxy-poly(ethylene) glycol.” International journal of pharmaceutics vol. 529,1-2 (2017): 75-86.
  • Abu-Fayyad, Ahmed, and Sami Nazzal. “Gemcitabine-vitamin E conjugates: Synthesis, characterization, entrapment into nanoemulsions, and in-vitro deamination and antitumor activity.” International journal of pharmaceutics vol. 528,1-2 (2017): 463-470.
  • Abu-Fayyad, Ahmed, and Sami Nazzal. “Extraction of Vitamin E Isomers from Palm Oil: Methodology, Characterization, and in Vitro Anti-Tumor Activity.” Journal of the American Oil Chemists' Society. (2017) 94: 1209.
  • Abu-Fayyad, Ahmed et al. “PEGylated γ-tocotrienol isomer of vitamin E: Synthesis, characterization, in vitro cytotoxicity, and oral bioavailability”. European Journal of Pharmaceutics and Biopharmaceutics, 96 (2015) 185-195.
  • Alayoubi, A. Abu-Fayyad, MM. Rawas-Qalaji, PW. Sylvester, and S. Nazzal. Effect of lipid viscosity and high- pressure homogenization on the physical stability of “Vitamin E” enriched emulsion. Pharm Dev Technol. 2015; 20(5):555-61.
  • Alayoubi, A. Abu-Fayyad, T. Al Hagbani, and S. Nazzal. The Parenteral Route: Simvastatin in Cancer Treatment. In:
    • Pais, C. Vitorino, and J. Sousa [eds.] Simvastatin Delivery: Challenges and Opportunities. Nova Science Publishers, Hauppauge, NY. 2015.
  • Alayoubi, A. Abu-Fayyad, and S. Nazzal. Vitamin E in Parenteral Lipid Emulsions. In: R. Rajendram, V. B. Patel and V. R. Preedy [eds.] Diet and Nutrition in Critical Care. Springer, New York, USA. 2015.

Lectures and Presentations

  • An Overview for some of the Translational Pharmaceutics Initiatives, University of Wyoming College of Pharmacy, March 2023
  • Lecture on Ophthalmics and a Discussion on Discovery, Clinical & Regulatory Pharmaceutics-based Product Development Initiatives, Western University of Health Sciences, College of Pharmacy, Feb 2023.
  • A Discussion on Discovery, Clinical & Regulatory Pharmaceutics-based Product Development Initiatives, St. John Fisher University College of Pharmacy, Feb 2023
  • Teaching in a new Pharm.D. program, William Cary University College of Pharmacy, Biloxi, MS, May 2017.
  • Novel Drug Delivery for Cancer Therapy, Hennepin Healthcare Research Institute- University of Minnesota Medical School, Minneapolis, MN, May 2017.
  • Vitamin E-based Drug Delivery Systems for Cancer Therapy, Fairleigh Dickinson University School of Pharmacy and Health Sciences, Florham Park, NJ, June 2017.

Honors/Awards

  • Teacher of the Year, College of Pharmacy, Chicago State University, Chicago, IL., 2019 - 2022
  • Best Research Poster Abstract Award in Pharmaceutics Section at the AACP 2021 Virtual Meeting, 2021
  • Preceptor of the Year Award, College of Pharmacy, Chicago State University, Chicago, IL., 2021
  • AACP Preceptor of the Year Award, American Association of Colleges of Pharmacy, Arlington, VA., 2021
  • Graduate Scholarship Endowment Award in Cancer Research, University of Louisiana, Monroe, LA., 2016

Memberships

  • American Association of Pharmaceutical Scientists (AAPS).
  • American Association of Colleges of Pharmacy (AACP).
  • Member of Arab American Association of Pharmaceutical Scientists.
  • Member of Arab American Pharmacy Educators (AAPE).