School of Health Professions & Nursing
Daniel Ginsburg, Ph.D.
Assistant Professor of Biomedical Sciences
Director, Laboratory of Gene Regulation
School of Health Professions and Nursing
A specialist in genetic research, Dr. Daniel Ginsburg is director of LIU Post's Laboratory of Gene Regulation, which studies the mechanisms by which human cells 'transcribe' a selection from the 23,000 potential genes encoded in our genome.
A graduate of Stanford University with a Ph.D. in genetics, Dr. Ginsburg was appointed assistant professor of biomedical sciences at Long Island University/LIU Post in 2010. In addition to teaching courses in the bachelor's and master's programs in biomedical technology, biomedical sciences, clinical laboratory science, medical biology and cardiovascular perfusion, he mentors select university and high school junior scientists in his campus laboratory.
Dr. Ginsburg's research is based on an understanding that even though all of the cells in one person contain the same DNA, different types of cells -- a brain cell, a liver cell, and a skin cell -- have different shapes and different functions. This is due to the fact that different genes are turned on or expressed in those different cells.
One step in the mechanism of gene expression is called transcription, synthesizing an RNA molecule from the common DNA template. One of the primary regulators of transcription is chromatin, the protein-DNA complex that makes up the chromosomes in eukaryotic cells. Chromatin limits what proteins have access to the DNA, so it must be altered for transcription to take place.
In Dr. Ginsburg's lab, researchers investigate how changes in chromatin and transcription are linked.
At Stanford University, Dr. Ginsburg worked on developing a tool for integrating new DNA into the genome at specific places. He participated in a postdoctoral fellowship at the National Institute of Child Health and Human Development (part of the NIH), where he started working on the same topics he continues with today.
In addition to laboratory research, Ginsburg is assistant professor in the Department of Biomedical Sciences, where he teaches students working toward the B.S. in Biomedical Technology, B.S. in Biomedical Sciences with Specialization in Clinical Laboratory Sciences, M.S. in Medical Biology, M.S. in Clinical Laboratory Science and M.S. in Cardiovascular Perfusion.